Allergy Diagnostics

All types of allergy diagnostics:

• drug allergy diagnostics
• to tree pollen (birch, alder, hazel, etc.)
• to pollen of cereal and meadow herbs (timothy grass, hedgehog team, chaff, ryegrass, etc.)
• to pollen of weeds (wormwood, ragweed, sunflower)
• to indoor allergens (house dust mites, mold fungi, in particular alternapia, storage space, acpergillus, yeast and others)
• to animals/pet allergens(cat, dog, hamster, rabbit, horse, sheep, guinea pig, parrot, feather of chicken and goose)
• insect allergy (allergy to insect venom)
• a wide range of food allergens, including molecular components of allergens

Skin Allergy Tests

Skin Allergy Tests for the following allergens are performed:

• pollen
• indoor
• epidermal
• food (including casein, lactoglobulin, gluten molecules)
• mold
• medicinal

Determination of specific immunoglobulins E

Screening tests:

• Screening panels for 20 allergens (children, adults, food, inhalation) RIDA Allergy Screen Panel
• Multicomponent molecular quantitative diagnostics of specific sIgE and total IgE by the Allergy Explorer ALEX allergy test (Austria) simultaneously to 282 allergens (160 extracts and 122 molecules)
• Determination of reaction to one allergen or allergen molecule
• Allergy tests (patch test) with dental materials - Dental panel (30 haptens)
• Test with autoserum for the diagnostics of chronic relapsing urticaria

Allergy tests (patch test) for allergies to chemicals - European panel (30 haptens)

Only in our center you can pass allergy tests (patch tests) with a set of the most common haptens recommended by the European Research Group on Environmental and Contact Dermatitis (EECDRG).

Using an allergy test (patch tests) it is possible to accurately determine the cause of contact dermatitis, as well as get differential diagnostics of allergic contact dermatitis, including metals (nickel and cobalt), as well as a number of chemical agents collected in the European panel S-1000.

What is a patch test?

• These are application skin tests (allergy tests) for diagnosing contact dermatitis.
• With the help of patch tests it is possible to accurately determine the cause of contact dermatitis, as well as get differential diagnostics of allergic contact dermatitis, including metals (nickel and cobalt), as well as a number of chemical agents collected in the European panel S-1000.

Patch Test Technique

A patch with a small amount of chemical is applied to the back skin in the area between the shoulder blades. The result is evaluated after 24–48 hours for an initial assessment of the reaction, which is carried out 30 minutes after removal of the patch test.

The test results are re-evaluated 48 hours after setting, then after 3 or 4 days and, if necessary, after 7 days.

If the patient has sensibilization to contact allergens or is allergic to dental materials, a local reaction is observed in the areas of skin contacting with them.

Preparing a patient for patch testing

The skin of the patient's back should be clean, without rashes, in order to avoid false-positive test results.

Stop administration topical or systemic glucocorticosteroids 2 days before the tests.

After setting an allergy test (patch test), it is necessary to avoid physical exertion (to avoid sweating) and not to wash for the duration of the test.

In our clinic the following allergens are available for allergy testing (patch testing):

Potassiumdichromate(chemical name) - used in the manufacture of cement, for tanning leather, in paints, dyes for textiles, preservatives for wood, alloys, matches, photographs, electroplating, anti-corrosion chemicals, lithography, ceramics, Xerox paper, tattoo inks, mascaras , waxes for a floor, cleaners for shoes, glues, detergents, etc (area of use).

p-PHENYLENEDIAMINE (PPD) - In the production of rubber, in reagents, hair and fur dyes, lithography, photocopy and photocopying materials, oils, gasoline, rubber, plastics, etc.

Thiurammix (Dipentamethylenethiuramdisulfide (PTD), Tetraethylthiuramdisulfide (TETD), Tetramethylthiuramdisulfide (TMTD), T etramethylthiurammonosulfide (TMTM) - Additives in rubber products - gloves, condoms, elastic bands, toys, kitchen utensils, shoes, clothes, tires, pipes, hoses, conveyor belts, electrical wiring, headphones, balloons), in adhesives, adhesives, animal repellents, cosmetic applicators, disinfectants means, medical devices, soap, in some agricultural products (fungicides, seed dressers), etc.

Neomycinsulfate - broad-spectrum antibiotic for local use (in the form of a cream, powder, ointment, eye and ear drops), in dental materials, veterinary medicine, etc.

Cobalt (II), chloridehexahydrate - dyes for glass, porcelain, ceramics, enamel, as a desiccant (drying agent) in paints, in nickel plating of metals, in metal alloys (dental, etc.), etc.

Benzocaine - local anesthetic in medicines: antihemorrhoidal creams, suppositories, sprays, lozenges for the oral cavity and gums, cough syrups, antiallergic and anti-burn agents, etc.

Nickel (II) sulfatehexahydrate - jewelry, buttons, clothing zips, pens, scissors, kitchen utensils, keys, razor, eyeglass frames, tools, devices, batteries, cutting fluids, coins, pigments, dentures, orthopedic plates, electrical wiring, etc.

Clioquinol - medicines: topical antibiotics, intravaginal for the treatment of trichomoniasis, veterinary drugs, antibacterial treatment of bandages, tissues, etc.

COLOPHONIUM - rosin: varnishes, paints, photo paper, plasticizers, fabrics, solder fluxes, lubricants, cutting fluid, glue, wax, protective coatings, insulation, cosmetics (mascara, blush, shadows), local medicines, shoes, dental filling materials and other

Paraben mix (BUTYLPARABEN, ETHYLPARABEN , METHYLPARABEN, PROPYLPARABEN) - preservatives in cosmetics (skin care, mascara, lipstick, toothpaste), in food products (jam, sweets, jellies, soft drinks, ketchup, fish packed), in medicines (creams, ointments, lotions, eye and ear drops , vaginal creams, antihemorrhoidal preparations), etc.

N-Isopropyl-N-phenyl-4- phenylenediamine (IPPD) - It is used to protect rubber from oxidation and cracking during bending, in gloves, shoes, grease, oils, etc.

LANOLIN ALCOHOL - in pharmaceutical and cosmetic products (medical shampoos, lotions, moisturizers and sunscreens, lipstick, makeup remover, shadows, varnishes, shaving creams, baby oils), printing inks, polishes, oils, leather products, paper, etc. .

Mercaptomix (N-Cyclohexyl-2- benzothiazolesulfenamide, 2- Mercaptobenzothiazole (MBT) Dibenzothiazyldisulfide (MBTS), 2-(4- Morpholinylmercapto) benzothiazol (MOR)) - impurities in the production of rubber products to improve their functions (gloves, condoms, shoes, hoses, tubes, tires), as anti-corrosion and disinfectants - for storing seeds, etc.

Epoxyresin, Bisphenol A - resin, in the composition of glue, electrical insulation, plasticizers, polymer stabilizers, laminate, paints, ink, ship varnish, PVC products, gaskets, vinyl gloves, materials for sculptures, etc.

Beechbalsam* (BalsamPeru) - flavoring in tobacco, drinks, confectionery, wine, liquor, spices, in medicines, toothpaste and rinse, perfumes, deodorants, aftershave, cosmetics, baby powders, sunscreens, shampoos, conditioners, soft drinks and etc.

4-tert-Butylphenolformaldehyde resin (PTBP) -. resin, in glue (adhesives) for leather products, rubber (shoes, bags, belts), paints, additives for motor oils, paints, paper, fiberglass, plywood, insulation, sealants, deodorants, disinfectants, etc.

2-Mercaptobenzothiazole (MBT) - (shoes, gloves, rubber bands in clothes, swimwear condoms, diaphragms, medical devices, hemodialysis equipment, toys, car tires, pipes), oils, antifreeze, lubricants, glues, washing emulsions, photochemicals veterinary preparations (against mites, anti-flea), etc.

FORMALDEHYDE - preservative, astringent and antiseptic in household products, cleaning products used in the manufacture of textiles, cosmetics (shampoos, deodorants), oil-cooling mixtures, pesticides, adhesives, shoes, dental plastics, wood, particle boards, mineral wool, paints, polishes , varnish, paper, embalming solution, fertilizer, reagents, insulation, etc.

Fragrance mix (CINNAMYL ALCOHOL, CINNAMAL, HYDROXYCITRONELLAL, AMYL CINNAMAL, GERANIOL, EUGENOL, ISOEUGENOL, Oakmoss absolute) - fragrances in perfumes, cosmetics and detergents, fabric softeners, air fresheners, toothpastes, other personal care products

Sesquiterpene lactone mix (Costunolide, Alantolactone, Dehydrocostus lactone) - in lotions, perfumes, cosmetics, topical medicines (ointments, creams), etc.

QUATERNIUM-15 - preservative in cosmetics (shampoos, rinses, lotions, creams, hygienic powder, products for manicure), in coolant, latex paints, varnishes, metalworking fluids, adhesives, paints, etc.

2-Methoxy-6-n-pentyl-4-benzoquinone - Primula plant substance, it is used as an antibacterial and antitumor component in topical drug products, etc.

METHYLISOTHIAZOLINONE + METHYLCHLOROISOTHIAZOLI NONE -  preservative in oils, coolants, soap, latex emulsions, in jet fuel, radiography, paints, wet toilet paper, detergents, cosmetics (shampoos, conditioners, gels, bath foams, creams, lotions, mascaras), etc.

Budesonide - glucocorticosteroid for local treatment of rhinitis, asthma, hay fever, hay fever, inflammatory bowel disease, etc. corticosteroid allergy marker

Tixocortol-21-pivalate - glucocorticosteroid for local treatment of rhinitis, pharyngitis, ulcerative colitis, etc. Group A Corticosteroid Allergy Marker

METHYLDIBROMO GLUTARONITRILE - preservative in cosmetics, topical medicines, adhesives, latex emulsions, dispersed dyes, detergents, wet toilet paper, fabric softeners, lubricants, coolants, products used for processing metals, wood, etc.

Fragrance mix II (Hexyl cinnamic aldehyde, HYDROXYISOH EXYL 3- CYCLOHEXENE CARBOXALDEHYDE, FARNESOL, COUMARIN, CITRAL, CITRONELLOL) - flavors used in most products: cosmetics, perfumes, detergents, washing liquid, for personal hygiene, etc.

CYCLOHEXENE CARBOXALDEHYDE - flavoring in alcohol lotions, antiperspirants, deodorants - sticks, washing powder, conditioners for fabrics, household detergents, shampoos, soaps, etc.

METHYLISOTHIAZOLINONE - biocide and preservative in cosmetics (shampoos, soap, body care products), coolants, etc.

Textile dye mix (Disperse Blue 35, Disperse Orange 1, DISPERSE ORANGE 3, Disperse Red 1, DISPERSE RED 17, Disperse Yellow 3, Disperse Blue 106, Disperse Blue 124) - a mixture of the most common textile and dispersed dyes for fabrics, clothes (nylon, acrylic), plastics in hair dyes, polyesters, etc.